Status:
COMPLETED
HEARD (Long Term) Study - Histology of the Esophagus in Acid-Related Disease
Lead Sponsor:
AstraZeneca
Conditions:
Gastroesophageal Reflux
Heartburn
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Determine if different levels of acid-suppression with esomeprazole for 6 months on chosen histological markers of esophageal epithelial acid-related disease in patients with upper GI symptoms.
Eligibility Criteria
Inclusion
- Signed informed consent
- 18 years or older
- history of upper GI symptoms
Exclusion
- Peptic ulcer disease
- upper gastrointestinal surgery
- malignancy
Key Trial Info
Start Date :
April 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2007
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT00243724
Start Date
April 1 2005
End Date
June 1 2007
Last Update
March 26 2009
Active Locations (10)
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1
Research Site
Vancouver, British Columbia, Canada
2
Research Site
Halifax, Nova Scotia, Canada
3
Research Site
Guelph, Ontario, Canada
4
Research Site
Hamilton, Ontario, Canada