Status:
COMPLETED
Efficacy Study of CDP870 in Subjects With Chronic Plaque Psoriasis Who Are Candidate for Systemic Therapy and/or Phototherapy/Photochemotherapy
Lead Sponsor:
UCB Pharma
Conditions:
Chronic Plaque Psoriasis
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
A study to assess the safety and efficacy of 2 different doses of CDP870 versus placebo, administered during 12 weeks, to patients suffering from moderate to severe chronic plaque psoriasis, extended ...
Eligibility Criteria
Inclusion
- Adult men and women \> 18 years
- Subjects with chronic plaque psoriasis stable for at least 3 months and moderate to severe for at least 6 months
- Subjects with Psoriasis Area and Severity Index (PASI) ≥ 12 and Body Surface Area (BSA) ≥ 10 %
- Subjects were candidates for systemic psoriasis therapy and/or phototherapy and/or photochemotherapy
Exclusion
- Subjects with an erythrodermic, guttate, palmar or plantar, generalized pustular form of psoriasis
- A history of chronic infection, recent serious or life-threatening infection (within six months, including herpes zoster), or any current sign or symptom that may indicate an infection (e.g. fever, cough);
- White blood cell counts less than 4000/mm\^3 or more than 20000/mm\^3
- Suspected or diagnosed demyelinating disease of the central nervous system (e.g. multiple sclerosis or optic neuritis)
- Systemic Lupus
- Non respect of adequate wash out periods for treatments that might have an impact on the disease
- Any associated disease that could be impacted by the study treatment intake
- Any other condition, which in the Investigator's judgment would make the subject unsuitable for inclusion in the study
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2006
Estimated Enrollment :
176 Patients enrolled
Trial Details
Trial ID
NCT00245765
Start Date
October 1 2005
End Date
November 1 2006
Last Update
May 3 2019
Active Locations (15)
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1
Besançon, France
2
Créteil, France
3
Nice, France
4
Paris, France