Status:
TERMINATED
Urinary Tract Infection Study With the Antibiotic Levofloxacin Given at a Higher Dose Over a Shorter Period of Time
Lead Sponsor:
University of Manitoba
Conditions:
Complicated Urinary Infection
Eligibility:
All Genders
18-80 years
Phase:
PHASE4
Brief Summary
The purpose of the study is to compare the safety and effectiveness of the antibiotic levofloxacin by administering a higher dose of levofloxacin and using a shorter course of therapy.
Detailed Description
This study will be a pilot study of the efficacy of 750 mg of levofloxacin once daily for 5 days in the treatment of complicated urinary tract infection. The specific objectives include: 1. To descr...
Eligibility Criteria
Inclusion
- Acute symptoms of urinary infection of less than 7 days duration and an underlying structural or functional abnormality of the genitourinary tract.
- Pre-therapy urine culture \> 105 cfu/ml (\> 108 cfu/L) of at least one urinary pathogen.
- Age 18-80 years, male or female.
Exclusion
- Prior allergic reaction to any fluoroquinolone antimicrobial.
- Known infection with a fluoroquinolone - resistant organism.
- Requiring parenteral therapy because of severity of illness or unable to take oral medications.
- Women who are pregnant or breastfeeding.
- Requiring additional antimicrobial therapy for infections elsewhere.
Key Trial Info
Start Date :
October 1 2004
Trial Type :
INTERVENTIONAL
End Date :
July 1 2005
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00245791
Start Date
October 1 2004
End Date
July 1 2005
Last Update
June 3 2015
Active Locations (3)
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1
St. Boniface General Hospital
Winnipeg, Manitoba, Canada, R2H 2A6
2
Health Sciences Centre
Winnipeg, Manitoba, Canada, R3A 1R9
3
University of Manitoba
Winnipeg, Manitoba, Canada, R3E 0W3