Status:
COMPLETED
Fibre and Appetite Regulation Trial (FART)
Lead Sponsor:
University of Toronto
Collaborating Sponsors:
Canadian Diabetes Association
Canadian Institutes of Health Research (CIHR)
Conditions:
Obesity
Diabetes
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
High intake of cereal fibre has been shown to be associated with reduced weight gain and improved insulin sensitivity. We hypothesize these effects are due to the short chain fatty acids derived from ...
Eligibility Criteria
Inclusion
- Non-diabetic male or non-pregnant females
- aged 18-60
- BMI\<36
- fasting insulin \>40pmol/L (70%ile)
Exclusion
- intention to lose \>5kg in weight
- presence of diabetes (fasting glucose \>6.9mmol/L)
- use of diuretics, beta-blockers or weight reducing drugs
- use of antibiotics in last 3 months and use of antibiotics more than once annually for the last 2 years
- significant gastrointestinal, liver or kidney disease
- use of lipid-lowering drug
- major medical or surgical event in last 6 mo.
- fibre intake \>30g/d
- inability to eat low or high fibre breakfast cereals
- unwilling or unable to give consent or comply with protocol
Key Trial Info
Start Date :
March 1 2002
Trial Type :
INTERVENTIONAL
End Date :
August 1 2005
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT00247455
Start Date
March 1 2002
End Date
August 1 2005
Last Update
June 21 2011
Active Locations (1)
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1
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8