Status:
WITHDRAWN
Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
Lead Sponsor:
Johns Hopkins University
Conditions:
Familial Adenomatous Polyposis
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to assess if curcumin, a commonly used food spice, can regress colorectal adenomatous polyps in patients with familial adenomatous polyposis, an inherited form of colorect...
Eligibility Criteria
Inclusion
- Familial adenomatous polyposis
- 18 years of age or older
- 5 or more adenomas of colorectum or ileum
Exclusion
- Female patient of child bearing age not on effective birth control pills
- Pregnant women
- White blood cell (WBC) count less than 4000
- Platelets (Plts) less than 100,000
- Blood urea nitrogen (BUN) greater than 25
- Creatine greater than 1.5
- Patients unable to stop non-steroidal anti-inflammatory drugs (NSAIDs) during duration of trial
- Malignancy
- Patient with active bacterial infections of gastroesophageal reflux disease or peptic ulcer disease
- Patient on warfarin or anti-platelet drugs
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00248053
Start Date
November 1 2005
Last Update
September 20 2012
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