Status:

COMPLETED

Aggrastat to Zocor (AtoZ) - the Use of Two Approved Drugs to Treat Patients Who Have Experienced Chest Pain or a Heart Attack (0733-180)

Lead Sponsor:

Organon and Co

Conditions:

Acute Coronary Syndrome

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

A-Phase: Evaluating patients with chest pain who are receiving approved drugs, to estimate the effectiveness of one type of blood thinner as compared to another type of blood thinner. Z-Phase: To eva...

Eligibility Criteria

Inclusion

  • A-Phase: Chest pain at rest for 10 minutes, EKG changes or elevated cardiac blood work
  • Z-Phase: elevated cholesterol , plus at least one risk factor ( \> 70 years old, diabetes, history of prior heart or blood vessel disease, chest pain with EKG changes, elevation of cardiac lab work or positive cardiac tests , at least 2 heart vessels blocked \[one \>= 75% and one \>= 50%\])

Exclusion

  • A-Phase: use of some specific cardiac drugs, high risk bleeding, prior blood clotting disorders
  • Z-Phase: elevation in certain cardiac blood tests, no significant heart damage at catheterization, planned cardiac surgery or specific cardiac drugs that lower cholesterol levels, within 6 weeks of enrollment

Key Trial Info

Start Date :

November 1 1999

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 23 2004

Estimated Enrollment :

4497 Patients enrolled

Trial Details

Trial ID

NCT00251576

Start Date

November 1 1999

End Date

March 23 2004

Last Update

August 15 2024

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