Status:
COMPLETED
The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular Disease
Lead Sponsor:
Bispebjerg Hospital
Conditions:
Diabetes Mellitus
Hypertension
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate whether a daily intake of dried broccoli sprouts will improve the endothelial function of the participants as measured by Flow mediated dilation (FMD) The ...
Detailed Description
Inflammation plays an important role in the development of atherosclerosis. The initial site of damage is the endothelium and secondarily the rest of the vascular wall is involved. Hypotheses concerni...
Eligibility Criteria
Inclusion
- Patients suffering from hypertension, having a diastolic blood pressure of above 90 mm Hg or a systolic blood pressure of more than 140 mm Hg.
- Patients suffering from NIDDM, according to present criteria for diagnosis of NIDDM:
- People with dyslipidemia (combination of total cholesterol above 5, LDL cholesterol above 3 and HDL cholesterol below 1.1)
- Healthy controls suffering from none of the above conditions, but otherwise (age, sex, BMI and lifestyle) corresponding to the patient groups.
Exclusion
- Patients under the age of 18 at inclusion in the study.
- Pregnant or breastfeeding women
- Women of childbearing age with no safe method of contraception
- Patients receiving vitamin K-antagonists (coumarine, marcoumar etc)
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2007
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT00252018
Start Date
January 1 2006
End Date
March 1 2007
Last Update
May 14 2008
Active Locations (1)
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1
Bispebjerg Hospital
Copenhagen, Denmark, 2400