Status:
TERMINATED
Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease
Lead Sponsor:
Children's Hospital of Philadelphia
Conditions:
Sickle Cell Disease
Eligibility:
All Genders
7-18 years
Phase:
PHASE4
Brief Summary
The purpose of this pilot study is to provide a preliminary assessment of the feasibility and efficacy of intravenous ketamine in controlling pain in patients with sickle cell disease (who are admitte...
Detailed Description
It is often difficult to manage acute painful crisis in patients with sickle cell disease. The usual management of these crises relies on hydration, administration of oxygen and narcotics, like morphi...
Eligibility Criteria
Inclusion
- Children ages 7 to \<19
- Acute vaso-occlusive crisis
- Persistent pain despite initial pain management with intravenous (IV) opioids
Exclusion
- Contraindications to the use of ketamine
- Mental retardation or psychological conditions that may affect the proper evaluation of pain and side effects
- Known allergy to ketamine
Key Trial Info
Start Date :
June 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2007
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT00252122
Start Date
June 1 2004
End Date
January 1 2007
Last Update
March 13 2009
Active Locations (1)
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1
The Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104