Status:
COMPLETED
Treatment of Bipolar Mania in Older Adults
Lead Sponsor:
Weill Medical College of Cornell University
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Bipolar Disorder
Mania
Eligibility:
All Genders
60+ years
Phase:
PHASE4
Brief Summary
This study will compare the benefits and side effects of lithium and divalproex in the treatment of older adults with bipolar mania.
Detailed Description
This is the first controlled acute treatment study of bipolar disorder in adults 60 years or older with current DSM-IV manic, mixed, or hypomanic episodes. The number of older adults with severe and d...
Eligibility Criteria
Inclusion
- Diagnosis of DSM-IV Bipolar Disorder, Type I: current manic, mixed, or hypomanic episodes
Exclusion
- Rapid cycling bipolar disorder
- History of substance abuse or dependence within last 3 months
- Diagnosis of schizophrenia or other chronic psychotic conditions
- Acute or unstable medical illness
- Documented intolerance to Lithium, Depakote, Risperidone, or Lorazepam
- Dementia
- Inability to communicate in English
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
224 Patients enrolled
Trial Details
Trial ID
NCT00254488
Start Date
November 1 2005
End Date
August 1 2011
Last Update
September 25 2018
Active Locations (8)
Enter a location and click search to find clinical trials sorted by distance.
1
Precise Research Centers
Flowood, Mississippi, United States, 39232
2
Weill Cornell Medical College
White Plains, New York, United States, 10605
3
Duke University Medical Center
Durham, North Carolina, United States, 27710
4
University Hospitals Case Medical Center
Cleveland, Ohio, United States, 44106