Status:
COMPLETED
Comparison of the Efficacy and Safety of Ivermectin to Permethrin
Lead Sponsor:
University Ghent
Conditions:
Scabies
Eligibility:
All Genders
5+ years
Phase:
PHASE2
Brief Summary
Comparison of the efficacy and safety of a single administration of ivermectin to a single administration of permethrin for the treatment of scabies
Detailed Description
Administration of ivermectin or permethrin on day0 Clinical examination and pictures on day0, day14 and day28 Blood sample on day0 VAS for pruritus, DLQI and SF-36 on day0, day14 and day28
Eligibility Criteria
Inclusion
- At least one of the following inclusion criteria:
- Scabies tunnels
- Positive microscopic examination (acarids, faeces or ova)
- At least two of the three following inclusion criteria:
- Non-specific injuries with a typical distribution pattern
- Serious itching which increases during the night
- Family or contacts with similar complaints
Exclusion
- Treatment for scabies \< 4 weeks ago
- Treatment with corticoids \< 1 week ago
- Pregnancy
- Breast-feeding
- HIV
- Serious immunodepressive patients
- Sensitivity or allergy to one of the components of the study medication
- Damage of the central nerve system
Key Trial Info
Start Date :
July 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2005
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT00262418
Start Date
July 1 2004
End Date
May 1 2005
Last Update
December 28 2007
Active Locations (1)
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1
University Hospital Ghent
Ghent, Belgium, 9000