Status:
COMPLETED
D-dimer Levels During and After Anticoagulation in Patients With a Previous Venous Thromboembolism: Effects on the Risk of Recurrence
Lead Sponsor:
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Collaborating Sponsors:
Italian Federation of Anticoagulation Clinics (FCSA)
Conditions:
Deep Vein Thrombosis
Pulmonary Embolism
Eligibility:
All Genders
18-82 years
Brief Summary
The results of the Prolong study, currently submitted for publication, show that patients with a first unprovoked venous thromboembolic event who have altered D-dimer levels, measured one month after ...
Eligibility Criteria
Inclusion
- Inclusion Criteria
- Age \> 18 years
- After a first documented idiopathic proximal deep vein thrombosis and/or pulmonary embolism
- After at least 6 months of oral anticoagulation
- After written informed consent
- Exclusion Criteria:
- Age \> 82 y
- Recurrent venous thromboembolism
- If the Venous thromboembolism occurred:
- during pregnancy or puerperium
- after recent (i.e. within three months) fracture or plaster casting of a leg,
- after immobilization with confinement to bed for three consecutive days after surgery with general anesthesia lasting longer than 30 minutes
- Patients with:
- active cancer
- antiphospholipid antibody syndrome
- antithrombin deficiency
- serious liver disease or renal insufficiency (creatininemia \> 2 mg/dL),
- other indications for anticoagulation or contraindications for this treatment
- limited life expectation
- Patients who live too far from the clinical center
Exclusion
Key Trial Info
Start Date :
August 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
355 Patients enrolled
Trial Details
Trial ID
NCT00266045
Start Date
August 1 2005
End Date
December 1 2008
Last Update
March 19 2021
Active Locations (1)
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1
Dept. Angiology & Blood Coagulation; Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi
Bologna, BO, Italy, 40138