Status:

COMPLETED

Airway Inflammation In Patients With Chronic Obstructive Pulmonary Disease

Lead Sponsor:

GlaxoSmithKline

Conditions:

Pulmonary Disease, Chronic Obstructive

Eligibility:

All Genders

40-80 years

Phase:

PHASE3

Brief Summary

This study was designed to look at effects of salmeterol/fluticasone propionate compared to placebo on airway inflammation in patients with chronic obstructive airways disease

Eligibility Criteria

Inclusion

  • Established clinical history of chronic obstructive airways disease.
  • Must be current or ex-smokers with a smoking history of at least 10 pack-years (e.g. 20 cigarettes/day for 10 years or 10 cigarettes/day for 20 years).
  • Must have reduced lung function, defined as a Forced Expiratory Volume in 1 second (FEV1) of between 40-80% of predicted normal values.

Exclusion

  • Diagnosis of any other serious disease and must have a chest X-ray to eliminate a diagnosis other than COPD.

Key Trial Info

Start Date :

October 1 2002

Trial Type :

INTERVENTIONAL

End Date :

December 1 2003

Estimated Enrollment :

130 Patients enrolled

Trial Details

Trial ID

NCT00268177

Start Date

October 1 2002

End Date

December 1 2003

Last Update

September 15 2016

Active Locations (20)

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Page 1 of 5 (20 locations)

1

GSK Investigational Site

Aalborg, Denmark, DK-9100

2

GSK Investigational Site

København NV, Denmark, 2400

3

GSK Investigational Site

Tallinn, Estonia, 13419

4

GSK Investigational Site

Tartu, Estonia, 51014