Status:
COMPLETED
Comparison of Vasopressin and Other Pressors in Septic Shock
Lead Sponsor:
Université de Sherbrooke
Conditions:
Shock, Septic
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to compare the classical tactics in the treatment of septic shock (dopamine, noradrenalin and dobutamine) to the use of vasopressin as first choice pressor. Vasopressin s...
Eligibility Criteria
Inclusion
- Legally major patient presenting a septic shock.
- The time window between beginning of symptoms and onset of treatment is established at 12 hours.
- The patient must be intubated and mechanically ventilated.
- Patient presenting a mean arterial blood pressure of less than 60 mm Hg after adequate fluid resuscitation (at least 1 L of colloid or crystalloid) and 10 ug/Kg/min of dopamine.
- Patient presenting a cardiac index of at least 3 L/min/m2
Exclusion
- Shock other than septic
- cardiac hypokinesia
- a pre-existing organic renal failure that needs hemodyalisis
- oesophagal or gastric phatology that would lead to a naso-gastric tube contraindication
Key Trial Info
Start Date :
July 1 2000
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00269685
Start Date
July 1 2000
Last Update
May 29 2006
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