Status:
COMPLETED
Efficacy of the Fentanyl Transdermal Therapeutic System (TTS) in the Management of Pain in Patients With Cancer
Lead Sponsor:
Alza Corporation, DE, USA
Conditions:
Pain
Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to evaluate the safety and effectiveness of continuous use of TTS fentanyl (a transdermal patch delivering the narcotic pain reliever fentanyl) for the treatment of chroni...
Detailed Description
Moderate to severe pain is experienced by about one-third of cancer patients during the intermediate stage of their disease. Currently used medications for the treatment of moderate to severe pain due...
Eligibility Criteria
Inclusion
- Patients with a diagnosis of intermediate stage of malignancy, operationally defined as non-localized or metastatic disease causing moderate to severe pain
- Having a diagnosis of terminal disease, defined as life expectancy of six months or less, with moderate to severe pain associated with malignancy
- Requiring treatment with a narcotic analgesic for relief of cancer pain
- Having normal liver, kidney, and lung function, as determined by liver function tests, BUN, creatinine, and blood gases
Exclusion
- Patients with a history of allergic reaction to narcotics
- Having a history of narcotic abuse prior to cancer diagnosis
- Unable to communicate adequately to provide information assessing the effectiveness of treatment
- Having active skin disease which precludes application of the transdermal system
- Having a history of carbon dioxide (CO2) retention or respiratory problems and who, in the physician's judgment, should not use narcotics
Key Trial Info
Start Date :
May 1 1986
Trial Type :
INTERVENTIONAL
End Date :
February 1 1988
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT00269737
Start Date
May 1 1986
End Date
February 1 1988
Last Update
May 19 2011
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.