Status:
TERMINATED
Benazepril for Advanced Chronic Renal Insufficiency
Lead Sponsor:
Southern Medical University, China
Conditions:
Chronic Kidney Failure
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to further determine whether benazepril, could safely slow the progression of renal dysfunction in non-diabetic patients with advanced renal insufficiency.
Eligibility Criteria
Inclusion
- serum creatinine concentration 1.5-5.0 mg/dL (133-442 µmol/L)
- creatinine clearance 20 to70 mL/min/1.73 m2, with variations of less than 30 percent in the three months before the screening evaluation
- non-diabetic renal disease
- persistent proteinuria (defined as urinary protein excretion greater than 0.3 g/day for three or more months without evidence of urinary-tract infection or overt heart failure \[New York Heart Association class III-IV\]).
Exclusion
- immediate need for dialysis; treatment with corticosteroids, non-steroidal anti-inflammatory drugs or immunosuppressive drugs; renovascular disease; myocardial infarction or cerebrovascular accident in the year preceding the trial; connective-tissue disease; obstructive uropathy.
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00270426
Last Update
May 5 2006
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