Status:
COMPLETED
Safety and Efficacy of MK0736 & MK0916 in Patients With Hypertension (High Blood Pressure)(0736-003)(COMPLETED)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Hypertension
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
The objective of this study is to evaluate the safety and efficacy of two investigational drugs (MK-0736 and MK-0916) in lowering blood pressure and body weight in patients with hypertension (high blo...
Detailed Description
Participants enrolled in the study will be separated into 2 strata based on baseline body mass index (BMI) assessments prior to being randomly assigned to study treatment. Study will include a 24-week...
Eligibility Criteria
Inclusion
- Hypertension systolic blood pressure (SBP) \</= 160mm Hg and diastolic blood pressure (DBP): 90-105mm Hg
Exclusion
- Pre-menopausal women
- patients currently taking more than two (2) blood pressure lowering medications
- Body Mas Index (BMI)\>40 kg/m2 (morbidly obese patients)
- History of Alcohol abuse (\<3 Years)
- History of diabetes,chronic kidney disease, Active liver disease, recent heart attack or stroke
Key Trial Info
Start Date :
November 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2007
Estimated Enrollment :
249 Patients enrolled
Trial Details
Trial ID
NCT00274716
Start Date
November 1 2005
End Date
January 1 2007
Last Update
July 3 2015
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