Status:
COMPLETED
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
Lead Sponsor:
Duke University
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Cardiovascular Diseases
Heart Diseases
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
Brief Summary
This study will investigate the separate and combined effects of aerobic and resistance training on cardiovascular risk factors in overweight men and women with mild to moderate dyslipidemia.
Detailed Description
BACKGROUND: Substantial evidence supports a favorable relationship between cardiovascular fitness, physical activity, and cardiovascular health. In particular, it is well established that increased l...
Eligibility Criteria
Inclusion
- Sedentary (exercises fewer than two times per week)
- Overweight or mildly obese (body mass index \[BMI\] of 25 to 35 kg/m2) with mild to moderate lipid abnormalities (either LDL cholesterol 130 to 190 mg/dl or HDL cholesterol less than 40 mg/dl for men or 5 less than 45 mg/dl for women)
Exclusion
- Diabetes
- Hypertension
- Other metabolic or musculoskeletal diseases
- Current use of or intent to diet
- Use of confounding medication
- Overt presence of coronary heart disease
- Unwilling to be randomized to any group
Key Trial Info
Start Date :
May 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
261 Patients enrolled
Trial Details
Trial ID
NCT00275145
Start Date
May 1 2004
End Date
December 1 2008
Last Update
May 24 2013
Active Locations (1)
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1
Duke University
Durham, North Carolina, United States, 27710