Status:

COMPLETED

A Comparison of the Drug Telbivudine (LdT) and Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis.

Lead Sponsor:

Mayo Clinic

Collaborating Sponsors:

Merck Sharp & Dohme LLC

Conditions:

Hepatitis B

Cirrhosis

Eligibility:

All Genders

18-70 years

Phase:

PHASE3

Brief Summary

This trial is being done to see if the investigational drug, LdT (Telbivudine), is safe and effective in the treatment of hepatitis B infection. In addition to this, we will be looking at the comparis...

Detailed Description

This study is a randomized, double-blinded trial looking at the drug Telbivudine (LdT) and comparing it to the drug lamivudine in patients with chronic hepatitis B and evidence of Cirrhosis. Interest...

Eligibility Criteria

Inclusion

  • Patients with chronic hepatitis b with evidence of cirrhosis, who are at least 18 to 70 years old, may be eligible to participate in this study.

Exclusion

    Key Trial Info

    Start Date :

    June 1 2004

    Trial Type :

    INTERVENTIONAL

    End Date :

    August 1 2007

    Estimated Enrollment :

    6 Patients enrolled

    Trial Details

    Trial ID

    NCT00275652

    Start Date

    June 1 2004

    End Date

    August 1 2007

    Last Update

    March 23 2011

    Active Locations (1)

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    Mayo Clinic

    Rochester, Minnesota, United States, 55905