Status:
COMPLETED
TNF Alpha in Refractory Asthma
Lead Sponsor:
University Hospitals, Leicester
Conditions:
Asthma
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The purpose of this study was to investigate whether the administration of etanercept to patients with severe asthma improved their asthma related quality of life and a measure of the degree of reacti...
Detailed Description
Although steroid dependent asthma represents a small population of patients with asthma, they consume a disproportionately large amount of the health resource burden attributed to asthma. Treatment op...
Eligibility Criteria
Inclusion
- Symptomatic asthma Methacholine PC20\<8mg/ml
Exclusion
- History of poor treatment concordance History of tuberculosis Radiographic evidence of previous tuberculosis Recent tuberculosis contact Respiratory tract infection within 3 months Current Smoker or Ex-smoker with more than 5 pack years Symptomatic co-morbid condition Contra-indication to etanercept Pregancy Breast feeding
Key Trial Info
Start Date :
December 1 2003
Trial Type :
INTERVENTIONAL
End Date :
September 1 2004
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00276029
Start Date
December 1 2003
End Date
September 1 2004
Last Update
May 4 2006
Active Locations (1)
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1
Institute for Lung Health
Leicester, Leicestershire, United Kingdom, LE3 9QP