Status:
UNKNOWN
Towards Restoring the Physiological Inhibition of Airway Narrowing in Asthma
Lead Sponsor:
Leiden University Medical Center
Collaborating Sponsors:
The Netherlands Asthma Foundation
Conditions:
Asthma
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
18-65 years
Brief Summary
Asthma and COPD are characterized by airway narrowing. The most potent, physiological mechanism leading to bronchodilation is taking a deep inspiration. This protects healthy subjects against bronchoc...
Detailed Description
Rationale. Asthma is associated with variable airways obstruction and airways inflammation. It is generally assumed that inflammatory mechanisms are promoting airway narrowing, by stimulating airway s...
Eligibility Criteria
Inclusion
- Asthma according to GINA criteria (www.ginasthma.org)
- COPD according to GOLD criteria (www.goldcopd.org)
Exclusion
- nonsmoking
- inhaled or oral steroid therapy
Key Trial Info
Start Date :
September 1 2004
Trial Type :
OBSERVATIONAL
End Date :
March 1 2006
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00279136
Start Date
September 1 2004
End Date
March 1 2006
Last Update
January 19 2006
Active Locations (1)
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1
Leiden University Medical Center
Leiden, Netherlands, NL-2300 RC