Status:

COMPLETED

TEDDY - The Environmental Determinants of Diabetes in the Young

Lead Sponsor:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsors:

National Institute of Allergy and Infectious Diseases (NIAID)

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Type 1 Diabetes Mellitus

Eligibility:

All Genders

Up to 4 years

Brief Summary

The long-term goal of the TEDDY study is the identification of infectious agents, dietary factors, or other environmental agents, including psychosocial factors which trigger T1DM in genetically susce...

Detailed Description

Epidemiologic patterns suggest that viruses, nutrition, toxic agents or socioeconomic psychosocial factors may contribute to the etiology alone or in combination. Elucidation is confounded by the long...

Eligibility Criteria

Inclusion

  • Newborns with high risk HLA in the general population or having a first- degree relative affected with T1DM
  • Newborns are less than 4 months of age

Exclusion

  • Have an illness or birth defect that precludes long-term follow-up or involves use of treatment that may alter the natural history of diabetes (e.g. steroids or insulin)
  • Refuses to have blood and stool samples stored at the NIDDK Repository

Key Trial Info

Start Date :

September 1 2004

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 30 2025

Estimated Enrollment :

8667 Patients enrolled

Trial Details

Trial ID

NCT00279318

Start Date

September 1 2004

End Date

June 30 2025

Last Update

September 22 2025

Active Locations (7)

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Page 1 of 2 (7 locations)

1

University of Colorado Health Sciences Center

Denver, Colorado, United States, 80262

2

Augusta University

Gainesville, Florida, United States, 32608

3

Augusta University

Augusta, Georgia, United States, 30912

4

Pacific Northwest Research Institute

Seattle, Washington, United States, 98122