Status:
TERMINATED
Treatment of Rhinitis With Intranasal Vitamin E
Lead Sponsor:
Milton S. Hershey Medical Center
Conditions:
Rhinitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Many beneficial effects of vitamin E have been described, but vitamin E supplementation by mouth has not been effective in the treatment of nasal symptoms and allergic rhinitis. The investigators will...
Detailed Description
Vitamin E has health promoting properties that are attributed to its anti-oxidant action and its ability to stabilize cell membrane and promote restoration of the skin barrier function. The beneficial...
Eligibility Criteria
Inclusion
- Clinical symptoms of rhinitis and symptom severity score of 25 or higher on the self-administered Rhinosinusitis Questionnaire (range of 0, i.e. absence of any symptom, to 50, which indicates the most severe symptom in each category)
Exclusion
- Inability to give informed consent, comprehend questions or instructions and complete questionnaires
- Recent change (within 2 weeks) in the medications that may affect nasal or sinus symptoms (intranasal or systemic glucocorticosteroids, mast cell stabilizer, antihistamines, decongestants, leukotriene antagonist, antibiotics, preparations containing thyroid or sex hormones, alpha-blocking agents)
- Intranasal use of oil- or gel-based products
Key Trial Info
Start Date :
December 7 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2007
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00281307
Start Date
December 7 2005
End Date
September 1 2007
Last Update
July 18 2017
Active Locations (1)
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1
Cathy Mende, CRNP
Hershey, Pennsylvania, United States, 17033