Status:
COMPLETED
Urinary Aquaporin 2 Excretion After Methylprednisolone in Fasting Healthy Humans
Lead Sponsor:
Regional Hospital Holstebro
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
We wanted to test the hypotheses that methylprednisolone up regulates u-AQP-2 in fasting healthy humans
Eligibility Criteria
Inclusion
- (1) Genders; both mal and female
- (2) Age; 18- 65 years old
- (3) BMI; below 30
- (4) Females had to bee in oral contraceptive treatment
Exclusion
- (1) Clinical signs or history of disease in the heart, lungs, kidneys or endocrine organs
- (2) Abnormal laboratory test (blood haemoglobin, white cell count, platelets, plasma sodium, plasma potassium, plasma creatinine, plasma albumin, plasma bilirubin, plasma alanine aminotransferase, plasma cholesterol and blood glucose)
- (3) Albuminuria or glucosuria
- (4) Cancer
- (5) Arterial hypertension
- (6) Alcohol abuse
- (7) Use of tobacco
- (8) Medical treatment, except oral contraceptives
- (9) Pregnancy or breast feeding
- (10) Medicine abuse
- (11) Donation of blood less than 1 month before the study.
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
End Date :
February 1 2007
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00281710
Start Date
October 1 2005
End Date
February 1 2007
Last Update
May 9 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Medicine, Holstebro Hospital
Holstebro, Denmark