Status:
COMPLETED
Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for Cancer
Lead Sponsor:
Case Comprehensive Cancer Center
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Neurotoxicity
Unspecified Adult Solid Tumor, Protocol Specific
Eligibility:
All Genders
21-85 years
Brief Summary
RATIONALE: Learning about the effects of chemotherapy and biological therapy on nerve function may help doctors plan treatment and help patients live more comfortably. PURPOSE: This clinical trial is...
Detailed Description
OBJECTIVES: * Determine the change in peripheral nerve function in cancer patients during and after treatment with chemotherapy or biologic therapy. * Determine the clinical measurement of hearing-re...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Histologically confirmed diagnosis of cancer
- Scheduled to be treated with 1 of the following agents:
- Cisplatin/paclitaxel combination
- Biologic therapy with high-dose interferon alfa
- PATIENT CHARACTERISTICS:
- Normal vision OR vision corrected with glasses or contact lenses
- No diseases or disorders reducing peripheral nerve function, including any of the following:
- Diabetes mellitus
- HIV/AIDS
- Uremia
- Spinal injuries
- Alcoholism
- CNS problems
- No hearing impairment
- PRIOR CONCURRENT THERAPY:
- No prior biologic therapy or neurotoxic chemotherapy
Exclusion
Key Trial Info
Start Date :
March 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 1 2007
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00281853
Start Date
March 1 2005
End Date
August 1 2007
Last Update
June 11 2010
Active Locations (1)
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1
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States, 44106-5065