Status:

COMPLETED

High-protein and High-carbohydrate Diets' Effect on Urinary Concentrating Ability

Lead Sponsor:

Regional Hospital Holstebro

Conditions:

Healthy

Eligibility:

All Genders

18-65 years

Phase:

PHASE4

Brief Summary

We wanted to test urinary concentrating ability and AQP-2 expression in kidney during high-protein and high-carbohydrate diet.

Eligibility Criteria

Inclusion

  • (1) Genders; both mal and female
  • (2) Age; 18- 65 years old
  • (3) BMI; below 30
  • (4) Females had to bee in oral contraceptive treatment

Exclusion

  • (1) Clinical signs or history of disease in the heart, lungs, kidneys or endocrine organs
  • (2) Abnormal laboratory test (blood haemoglobin, white cell count, platelets, plasma sodium, plasma potassium, plasma creatinine, plasma albumin, plasma bilirubin, plasma alanine aminotransferase, plasma cholesterol and blood glucose)
  • (3) Albuminuria or glucosuria
  • (4) Cancer
  • (5) Arterial hypertension
  • (6) Alcohol abuse
  • (7) Use of tobacco
  • (8) Medical treatment, except oral contraceptives
  • (9) Pregnancy or breast feeding
  • (10) Medicine abuse
  • (11) Donation of blood less than 1 month before the study.

Key Trial Info

Start Date :

May 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2009

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00282321

Start Date

May 1 2007

End Date

June 1 2009

Last Update

February 22 2010

Active Locations (1)

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Department of Medicine, Holstebro Hospital

Holstebro, Denmark