Status:

COMPLETED

New Strategies for Non-invasive Detection of Chronic Allograft Nephropathy

Lead Sponsor:

Virginia Commonwealth University

Collaborating Sponsors:

Hoffmann-La Roche

Conditions:

Chronic Rejection

Eligibility:

All Genders

18-70 years

Brief Summary

The purpose of this study is to help researchers find out more about a condition called "Chronic Allograft Nephropathy" (CAN). CAN is a complication that sometimes occurs after kidney transplantation ...

Detailed Description

We hypothesize that patients with CAN will manifest different patterns of gene expression profiling (compared with non-CAN controls), detectable in peripheral blood mononuclear cells (PBMCs) and urine...

Eligibility Criteria

Inclusion

  • Received primary kidney transplant Diagnosis of Chronic Allograft Nephropathy Stable immunosuppression for one month prior to entry

Exclusion

  • Serious comorbidity Pregnancy Retransplantation

Key Trial Info

Start Date :

January 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

121 Patients enrolled

Trial Details

Trial ID

NCT00283348

Start Date

January 1 2006

End Date

December 1 2008

Last Update

March 20 2017

Active Locations (1)

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1

VCU Health System

Richmond, Virginia, United States, 23298