Status:

TERMINATED

MYPROMS-ES02: Safety and Efficacy of Basiliximab, Cyclosporine Microemulsion and Enteric-coated Mycophenolate Sodium (EC-MPS) Versus EC-MPS and Steroid Therapy in Kidney Transplant Recipients Who Are Hepatitis C Positive

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

De Novo Kidney Transplant

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

To prospectively evaluate in de novo kidney transplant recipients, hepatitis C positive, the clinical outcomes of an immunosuppressive regimen of EC-MPS free of steroids in comparison with a regimen o...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • Patients hepatitis C positive (serology test within the last 12 months and determined by third-generation assay).
  • Recipients of heart-beating cadaveric, living unrelated or living related non-HLA identical donor kidney transplant, treated with basiliximab and CsA-ME as primary immunosuppression.
  • Exclusion criteria
  • Multi-organ recipients (e.g. double kidney, kidney and pancreas or kidney and liver) or previous transplant with any other organ.
  • Kidneys from non-heart beating donors.
  • ABO incompatibility against the donor.
  • Patients with panel reactive antibodies of \>50% at most recent assessment prior to transplantation and /or prior graft lost due to immunological reasons in the first six months post-transplantation or patients who are considered to be at increased risk of acute rejection by the principal investigator Additional protocol defined inclusion/exclusion criteria may apply.

Exclusion

    Key Trial Info

    Start Date :

    April 1 2004

    Trial Type :

    INTERVENTIONAL

    End Date :

    Estimated Enrollment :

    60 Patients enrolled

    Trial Details

    Trial ID

    NCT00284921

    Start Date

    April 1 2004

    Last Update

    November 2 2011

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