Status:
COMPLETED
Japan Morning Surge-1 Study
Lead Sponsor:
Japan Heart Foundation
Conditions:
Hypertension
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
The purpose of this study is to examine whether strict blood pressure (BP) control by doxazosin using home BP monitoring, especially targeting the morning BP level, can reduce hypertensive target orga...
Detailed Description
Morning blood pressure may play an important role in the pathogenesis of hypertensive target organ damage. Increased sympathetic nerve activity is reported to be one of the mechanisms of morning hyper...
Eligibility Criteria
Inclusion
- Morning systolic blood pressure \>135 mmHg in a sitting position at home while on stable antihypertensive medication for at least 3 months
Exclusion
- History of heart failure
- Presence of orthostatic hypotension, dementia, malignancy and chronic inflammatory disease
- Taking an alfa-blocker or beta-blocker
- Atrial fibrillation or atrial flutter
Key Trial Info
Start Date :
August 1 2003
Trial Type :
INTERVENTIONAL
End Date :
August 1 2005
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT00285519
Start Date
August 1 2003
End Date
August 1 2005
Last Update
February 2 2006
Active Locations (1)
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1
Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine
Shimotsuke, Tochigi, Japan, 329-0498