Status:

WITHDRAWN

Metabolic Abnormalities in Hispanic Children With Cystic Fibrosis

Lead Sponsor:

University of Texas Southwestern Medical Center

Collaborating Sponsors:

Genentech, Inc.

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

7-17 years

Phase:

NA

Brief Summary

Our specific aims include: 1. AIM 1. Characterization of glucose tolerance, nutritional and clinical status, socioeconomic status, family history of diabetes and genotype in Hispanic CF children comp...

Detailed Description

We will recruit 12 Hispanic prepubertal children with CF (ages 7-12, Tanner I) and 12 Hispanic adolescents (ages 15-17, Tanner 3 or 4) from the CF Centers at University of Texas Southwestern and Baylo...

Eligibility Criteria

Inclusion

  • Subjects will be required to be medically stable at the time of the study. Medical stability will be defined as:
  • No hospital admission for six weeks or more before the study
  • No oral or intravenous antibiotics for at least six weeks preceding the study (subjects will be allowed to use low doses of inhaled corticosteroids)
  • Weight-stable (weight deviation less than 2.5 kilograms) for two months prior to the study.

Exclusion

  • Use of oral or intravenous corticosteroid medications within six weeks of the study
  • Evidence of severe liver disease (hepatomegaly, 30% or greater elevation of liver transaminases, listed for liver transplant)
  • Colonization with Burkholderia cepacia
  • Pregnancy
  • Patients requiring supplemental oxygen.

Key Trial Info

Start Date :

February 2 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 2 2006

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00287443

Start Date

February 2 2006

End Date

February 2 2006

Last Update

December 26 2018

Active Locations (1)

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1

Children's Medical Center of Dallas

Dallas, Texas, United States, 75390