Status:

UNKNOWN

Sirolimus Eluting Stenting in Acute Myocardial Infarction

Lead Sponsor:

San Camillo Hospital, Rome

Conditions:

Myocardial Infarction

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The incidence of stent restenosis in the setting of primary angioplasty is particularly high, reaching a rate of 27% In the last years the introduction of drug-eluting stents has drastically reduced t...

Detailed Description

The treatment of acute myocardial infarction has evolved dramatically in the last decade. Coronary angioplasty with stent implantation in conjunction with an optimal antitrombotic therapy as abciximab...

Eligibility Criteria

Inclusion

  • Inclusion criteria were an age of more than 18 years, the presence for at least 30 minutes but less than 12 hours of symptoms consistent with acute myocardial infarction, and the presence of ST-segment elevation in at least two contiguous leads or left bundle-branch block.
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Exclusion

  • Patients were excluded if they were in cardiogenic shock (defined as systolic blood pressure of less than 80 mm Hg for more than 30 minutes or the need for intravenous pressors or intraaortic-balloon counterpulsation); had a history of bleeding diathesis; had a history of leukopenia, thrombocytopenia, or severe hepatic or renal dysfunction; had a noncardiac illness associated with a life expectancy of less than one year; were participating in another study; or were unable to give informed consent owing to prolonged cardiopulmonary resuscitation.
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Key Trial Info

Start Date :

March 1 2003

Trial Type :

INTERVENTIONAL

End Date :

March 1 2006

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00288210

Start Date

March 1 2003

End Date

March 1 2006

Last Update

February 10 2006

Active Locations (1)

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1

Cardiologia Interventistica Ospedale San Camillo

Roma, Roma, Italy, 00100