Status:

COMPLETED

Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024)

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Mixed Hyperlipidemia

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

This is a 12-week clinical trial in participants with mixed hyperlipidemia to study the effects of MK-0524B on lipids.The primary hypothesis is that MK-0524B (dosed as MK-0524A coadministered with sim...

Eligibility Criteria

Inclusion

  • Participant 18 to 80 years of age with Mixed Hyperlipidemia with LDL-C between 130 and 190 mg/dL and Triglycerides between 150 and 500 mg/dL

Exclusion

  • Pregnant or lactating women, or women intending to become pregnant
  • Diabetes mellitus that is poorly controlled, newly diagnosed, or taking new or recently adjusted antidiabetic therapy (with the exception of ± 10 units of insulin)
  • Human immunodeficiency virus (HIV) positive
  • Any of the following within the past 3 months: heart attack, stoke, heart bypass surgery, unstable angina, angioplasty
  • Active or chronic liver disease

Key Trial Info

Start Date :

January 24 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 6 2010

Estimated Enrollment :

2340 Patients enrolled

Trial Details

Trial ID

NCT00289900

Start Date

January 24 2006

End Date

August 6 2010

Last Update

August 31 2018

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