Status:

COMPLETED

Efficacy and Safety of Fingolimod in Patients With Relapsing-remitting Multiple Sclerosis

Lead Sponsor:

Novartis

Conditions:

Relapsing-remitting Multiple Sclerosis

Eligibility:

All Genders

18-55 years

Phase:

PHASE3

Brief Summary

This study assessed the efficacy, safety, and tolerability of 2 doses of oral fingolimod (1.25 mg/day and 0.5 mg/day) compared to placebo in patients with relapsing-remitting multiple sclerosis (RRMS)

Eligibility Criteria

Inclusion

  • Male and female patients between ages 18-55 with a diagnosis of multiple sclerosis
  • Patients with a relapsing-remitting disease course
  • Patients with EDSS score of 0-5.5

Exclusion

  • Patients with other chronic disease of the immune system, malignancies, acute pulmonary disease, cardiac failure, etc.
  • Pregnant or nursing women
  • Other protocol-defined inclusion/exclusion criteria applied to this study.

Key Trial Info

Start Date :

January 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2009

Estimated Enrollment :

1272 Patients enrolled

Trial Details

Trial ID

NCT00289978

Start Date

January 1 2006

End Date

July 1 2009

Last Update

April 11 2012

Active Locations (115)

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Page 1 of 29 (115 locations)

1

The Queen Elizabeth Hospital

Woodville South, South Australia, Australia, 5011

2

North Gosford Private Hospital

Burrabil Avenue, Suite 17, Gosford, Australia, NSW 2250

3

Strategic Health Evaluators

Chatswood, Australia, 2067

4

St Vincent's Hospital Melbourne, Department of Clinical Neurosciences

Fitzroy, Australia, 3065 VIC