Status:

TERMINATED

Foley Catheter for Labor Induction in Women With Term and Near Term Membrane Rupture

Lead Sponsor:

University of Alabama at Birmingham

Conditions:

Fetal Membranes, Premature Rupture

Labor, Induced/IS

Eligibility:

FEMALE

12-55 years

Phase:

NA

Brief Summary

In women undergoing labor induction for membrane rupture at or near term, we are investigating the addition of a foley catheter placed in the cervix to standard therapy (oxytocin administration) to de...

Detailed Description

To compare the efficacy of a transcervical Foley catheter with concurrent oxytocin administration compared to oxytocin infusion alone for cervical ripening and labor induction in women with premature ...

Eligibility Criteria

Inclusion

  • Preterm rupture of membranes (PROM) (Rupture of membranes = pooling/ferning/nitrazine +) Rupture of membranes (ROM) for ≥1 hour prior to starting induction
  • Cervix ≤ 2 centimeters (cm)
  • Gestational age ≥ 34 weeks by best obstetric estimate and clinical management decision is delivery
  • Singleton gestation
  • Cephalic
  • Vertex well applied to cervix

Exclusion

  • Regular uterine contractions (contractions more frequent than every 5 minutes)
  • Two prior transverse uterine incisions/vertical uterine incision/ transmural myomectomy or any obstetric contraindication to labor
  • Evidence of chorioamnionitis (temperature of 100.4°F with uterine tenderness and maternal or fetal tachycardia or purulent discharge)
  • Lethal fetal anomalies
  • Intrauterine fetal demise (IUFD)
  • Previa
  • Suspected abruption/significant hemorrhage
  • Non-reassuring fetal heart rate (FHR) pattern
  • Non vertex fetal presentation

Key Trial Info

Start Date :

December 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2008

Estimated Enrollment :

169 Patients enrolled

Trial Details

Trial ID

NCT00290199

Start Date

December 1 2005

End Date

May 1 2008

Last Update

May 23 2017

Active Locations (3)

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Page 1 of 1 (3 locations)

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35249

2

Christiana Care Health System

Newark, Delaware, United States, 19713

3

Greenville Hospital System University Medical Center

Greenville, South Carolina, United States, 29605