Status:
COMPLETED
Myocardial Regeneration and Angiogenesis in Myocardial Infarction With G-CSF and Intra-Coronary Stem Cell Infusion-3-DES
Lead Sponsor:
Seoul National University Hospital
Conditions:
Myocardial Infarction
Eligibility:
All Genders
Up to 80 years
Phase:
PHASE2
Brief Summary
This trial was performed to evaluate the safety of G-CSF based stem cell therapy and to compare outcome of intracoronary infusion of mobilized PBSCs between patients with AMI and OMI.
Detailed Description
The MAGIC Cell-DES trial was designed as a randomized, controlled trial to recruit 100 patients with AMI and OMI. Patients who were successfully revascularized with DES in the culprit lesion were elig...
Eligibility Criteria
Inclusion
- Patients with acute or old myocardial infarction who were successfully revascularized with DES in the culprit lesion were eligible for enrollment.
Exclusion
- 1\) Persistent severe heart failure (left ventricular ejection fraction (LVEF) \< 20%) 2) Uncontrolled myocardial ischemia or ventricular tachycardia 3) Culprit lesion of infarct related artery not feasible for percutaneous coronary intervention (PCI) or unsuccessful PCI 4) Age \> 80 years 5) Malignancy 6) Serious current infection or hematologic disease; and 7) Life expectancy under one year.
Key Trial Info
Start Date :
March 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2007
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT00291629
Start Date
March 1 2004
End Date
August 1 2007
Last Update
September 10 2007
Active Locations (1)
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1
Seoul National University Hospital, Yon-Gon Dong, Chongno-Gu
Seoul, Seoul, South Korea, 110-744