Status:
UNKNOWN
Differences in Human Germinal Center B Cell Selection Revealed by Analysis of IgVH Gene Hypermutation and Lineage Trees in Inflammatory Bowel Disease
Lead Sponsor:
Sheba Medical Center
Conditions:
Inflammatory Bowel Disease
Eligibility:
All Genders
Brief Summary
Our overall objective in this study is to study the role of B cells in inflammatory bowel disease (IBD), using a combination of high-throughput experimental and novel bioinformatical techniques. Idio...
Detailed Description
1. Extraction of Ig gene sequences from IBD patient gut samples. The proposed study aims to elucidate the role of B cells in IBD via investigating their Ig gene diversification. Hence the first step s...
Eligibility Criteria
Inclusion
- Inflammatory Bowel Disease
- Underwent colonic biopsies
Exclusion
- Other diseases
Key Trial Info
Start Date :
September 1 2005
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00291681
Start Date
September 1 2005
Last Update
February 14 2006
Active Locations (2)
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1
Department of Pathology
Tel Litwinsky, Israel, 52621
2
Iris Barshack, Department of Pathology
Tel Litwinsky, Israel, 52621