Status:
COMPLETED
Curing Atrial Fibrillation in Heart Failure
Lead Sponsor:
NHS Greater Glasgow and Clyde
Conditions:
Chronic Heart Failure
Atrial Fibrillation
Eligibility:
All Genders
16+ years
Phase:
NA
Brief Summary
Heart failure is a condition that occurs when the heart muscle weakens and no longer contracts normally. Half of these patients have an irregularity of heart rhythm called atrial fibrillation (AF). Pa...
Eligibility Criteria
Inclusion
- Informed consent
- Persistent atrial fibrillation (AF)
- New York Heart Association (NYHA) II, III and IV chronic heart failure (CHF) despite optimal medical therapy for at least 3 months
- left ventricular ejection fraction (LVEF) \<35% - as measured by radionuclide ventriculography (RNVG)
- Patients with CHF secondary to ischaemic and non-ischaemic aetiology
Exclusion
- QRS duration \>150ms (or QRS 120-150 with evidence of mechanical cardiac dysynchrony)
- Magnetic resonance imaging (MRI) - incompatible metallic (ferrous) prosthesis
- Primary valvular disease as a cause of CHF
- Reversible causes of CHF
- Acute myocarditis
- Patients aged 18 or less
- Patients having undergone revascularisation procedures within 6 months
- Paroxysmal AF
- Pregnancy
- Expected cardiac transplantation within 6 months
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT00292162
Start Date
January 1 2007
End Date
July 1 2009
Last Update
June 1 2012
Active Locations (1)
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1
Glasgow Royal Infirmary
Glasgow, Scotland, United Kingdom, G31 2ER