Status:

COMPLETED

A Trial Comparing Different Dosing Regimens of Morphine in Patients With Moderate to Severe Pain

Lead Sponsor:

Montefiore Medical Center

Conditions:

Pain

Eligibility:

All Genders

21-65 years

Phase:

NA

Brief Summary

RESEARCH QUESTION: In adult ED patients in whom the attending ED physician has decided to administer intravenous opiates, what is the difference in pain relief at 60 minutes in patients who are random...

Detailed Description

RESEARCH QUESTION: In adult ED patients in whom the attending ED physician has decided to administer intravenous opiates, what is the between-group difference in before-after improvement in pain relie...

Eligibility Criteria

Inclusion

  • Patients 21 to 65 years of age presenting to the ED with pain of less than or equal to 7 days duration and deemed by the ED attending to require opioid analgesia are eligible for inclusion.

Exclusion

  • Inability or unwillingness to provide informed consent, methadone use, use of other opioids or tramadol within 7 days, prior adverse reaction to morphine, chronic pain syndrome, alcohol intoxication, pregnancy or breast-feeding, systolic blood pressure \<90 mm Hg, use of MAO inhibitors, and weight greater than 100 kg.

Key Trial Info

Start Date :

March 1 2005

Trial Type :

INTERVENTIONAL

End Date :

January 1 2006

Estimated Enrollment :

280 Patients enrolled

Trial Details

Trial ID

NCT00293969

Start Date

March 1 2005

End Date

January 1 2006

Last Update

February 20 2006

Active Locations (1)

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1

Montefiore Medical Center Emergency Department

The Bronx, New York, United States, 10467