Status:
UNKNOWN
Genetic Variation and Immune Responses After Injury
Lead Sponsor:
National Institute of General Medical Sciences (NIGMS)
Conditions:
Sepsis
Pneumonia
Eligibility:
All Genders
Brief Summary
Our overall hypothesis is that genetic variations in innate immunity genes predispose patients to varying responses after injury by altering the systemic and local inflammatory responses. In addition,...
Detailed Description
The goal of this research proposal is to identify relationships that exist between specific genetic markers, immune responses to injury and infection (sepsis), and post injury clinical outcomes. Speci...
Eligibility Criteria
Inclusion
- All burn,trauma, or acute surgery victims admitted to the surgical, burn or trauma units within 24 hours of injury will be considered for inclusion.
Exclusion
- severe immunosuppression, DNR, severe trauma, terminal diseases.
- \-
Key Trial Info
Start Date :
August 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2011
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT00294697
Start Date
August 1 2003
End Date
October 1 2011
Last Update
August 24 2010
Active Locations (1)
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1
UT Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390-9160