Status:
COMPLETED
Doxazosin Effects on ABPM in Hypertensive Patients With Diabetic Nephropathy
Lead Sponsor:
Yokohama City University Medical Center
Conditions:
Diabetes Mellitus
Essential Hypertension
Eligibility:
All Genders
20-79 years
Phase:
PHASE4
Brief Summary
Few studies have reported the effect of alpha1-adrenergic antagonists on 24-h blood pressure and regulation of sympathetic nervous activity in hypertensive patients with diabetic nephropathy. Using am...
Detailed Description
The study is an open-labeled parallel prospective trial comparing the effects of doxazosin (2-8 mg/day) on 24-h blood pressure and autonomic nervous activity. Hypertensive patients with non-insulin-de...
Eligibility Criteria
Inclusion
- Hypertensive patients with diabetes mellitus
- Hypertensive patients
- Hypertensive patients with renal disease
Exclusion
- Cardiac, hematologic or hepatic disease
- Renal insufficiency (serum creatinine values\> 2 mg/L)
- Hormone-induced hypertension
- Cerebral infarction or hemorrhage
- Other major diseases
Key Trial Info
Start Date :
January 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2007
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT00295555
Start Date
January 1 2004
End Date
April 1 2007
Last Update
May 10 2007
Active Locations (1)
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1
Yokohama City University Center Hospital
Yokohama, Japan, 232-0024