Status:
COMPLETED
Treatment of Depression Following Multiple Brain Tests
Lead Sponsor:
New York State Psychiatric Institute
Conditions:
Major Depression
Dysthymia
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The main purpose of this study is to correlate brain testing with treatment outcome.
Detailed Description
40 medication-free Depressed Patients will receive a battery of neuropsychologic tests, standard dichotic listening tests, EEG, ERP and an f-MRI while performing a neuropsychologic test, the Simon. On...
Eligibility Criteria
Inclusion
- DSM-IV Major Depression or Dysthymia
- Age 18-65
- Physically healthy
- Normal hearing
- Drug-free (two weeks for most antidepressants, four weeks for Fluoxetine)
Exclusion
- Hearing deficit in one or both ears
- Body metal (e.g., wire stitches, screws in bones, stainless steel hips)
- History of Psychosis or Epilepsy
- Current (past six months) Substance Use Disorder (illicit drugs and/or alcohol)
- Unstable medical problem
- Insufficient English for neuropsychological and dichotic testing
- Bipolar I
- Need for wash-out from effective treatment in order to participate
- Pregnant
- High suicide risk
- Currently taking (within 2 weeks; 4 weeks for Fluoxetine) antidepressants
Key Trial Info
Start Date :
December 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT00296777
Start Date
December 1 2004
End Date
December 1 2007
Last Update
April 27 2012
Active Locations (1)
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1
Depression Evaluation Service - New York State Psychiatric Institute
New York, New York, United States, 10032