Status:

UNKNOWN

Effect of Folic Acid Treatment in Coronary Artery Disease

Lead Sponsor:

University of Oxford

Collaborating Sponsors:

British Heart Foundation

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

We seek to examine the effects of folic acid treatment on vascular function in patients with coronary artery disease. Our hypothesis is that folic acid treatment will improve vascular function

Detailed Description

Common vascular disease states including diabetes and atherosclerosis are associated with endothelial dysfunction, characterised by reduced bioactivity of nitric oxide (NO). Folates are thought to imp...

Eligibility Criteria

Inclusion

  • Clinical diagnosis of coronary artery disease

Exclusion

  • Recent acute coronary event Renal and/or hepatic dysfunction Metallic implants

Key Trial Info

Start Date :

May 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00300352

Start Date

May 1 2004

Last Update

August 7 2008

Active Locations (1)

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1

University of Oxford

Oxford, United Kingdom, OX3 9DU