Status:
COMPLETED
Effect of Continuous Positive Airway Pressure (CPAP) on Systemic Blood Pressure, Coagulability and Carotid Intima-media Thickness in Patients With Sleep Apnea
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Obstructive Sleep Apnoea
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
Sleep-disordered breathing (SDB) briefly means cessation of breathing during sleep at least 5 times per hour. Sleep-disordered breathing affects 9 to 24% of the middle-aged and overall 4% of the middl...
Detailed Description
Subjects and Methods: We propose to carry out a prospective, randomized controlled study on 100 consecutive patients newly diagnosed with obstructive sleep apnea syndrome, as defined by overnight slee...
Eligibility Criteria
Inclusion
- Age 20 to 80 yrs
- Apnoea Hypopnea index ≥5/hr on Polysomnography with Epworth Sleepiness Scale ≥10
Exclusion
- Predominantly central sleep apnoea
- Recent myocardial infarction 3 months before the study
- Unstable angina
- Underlying malignancy
- Professional drivers and those handling dangerous machinery
- Patients will be considered dropouts if anti-hypertensive medication is accidentally changed by the patients or their general practitioners
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 6 2019
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00300599
Start Date
January 1 2006
End Date
August 6 2019
Last Update
July 22 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The Chinese University of Hong Kong
Hong Kong, New Territories, Hong Kong