Status:

COMPLETED

Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia

Lead Sponsor:

Vilnius University

Conditions:

Opiate Dependence

Eligibility:

All Genders

18-35 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to determine whether low-dose ketamine infusion is effective in suppressing the symptoms of opiate withdrawal during rapid opiate antagonist induction (RAI).

Eligibility Criteria

Inclusion

  • Diagnosed opiate dependence according to ICD 10 and/or DSM 4;
  • Duration of substance abuse more than 1 year
  • No or minor co-morbidities;
  • Grade I-II according to physical status classification system of American Society of Anesthesiologists.

Exclusion

  • Current history of long acting opiate or poly-substance abuse;
  • Acute medical or surgical condition;
  • Pregnancy;
  • Breastfeeding.

Key Trial Info

Start Date :

February 1 2003

Trial Type :

INTERVENTIONAL

End Date :

June 1 2006

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00300794

Start Date

February 1 2003

End Date

June 1 2006

Last Update

November 14 2006

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Vilnius University Emergency Hospital

Vilnius, Lithuania