Status:
TERMINATED
Registry Study of Neoadjuvant Chemoradiation & Transplant for Cholangiocarcinoma Patients
Lead Sponsor:
Washington University School of Medicine
Conditions:
Cholangiocarcinoma
Eligibility:
All Genders
18+ years
Brief Summary
This is an observational study intended to validate results of a previous study done at the Mayo Clinic. Patients are treated with combination chemotherapy and radiation and maintained on oral Xeloda ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Diagnosis of cholangiocarcinoma that has been established preoperatively by at least one of the following criteria:
- A positive brush cytology or biopsy result obtained at the time of cholangiography;
- Fluorescence in situ hybridization demonstrating aneuploidy;
- A serum CA 19-9 value greater than 100 U/mL in the presence of a radiographically characteristic malignant stricture in the absence of cholangitis.
- Listed for OLT for hilar cholangiocarcinoma
- Tumor/stricture is above the cystic duct and is unresectable.
- A suitable candidate for orthotopic liver transplantation as judged by the liver transplant team. All 3 treatment modalities are not needed to confirm eligibility for this registry trial.
- \>/= 18 years of age.
- Willing and able to provide written informed consent.
Exclusion
Key Trial Info
Start Date :
August 12 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 6 2023
Estimated Enrollment :
59 Patients enrolled
Trial Details
Trial ID
NCT00301379
Start Date
August 12 2005
End Date
June 6 2023
Last Update
June 15 2023
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110