Status:
COMPLETED
Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Conditions:
Smoking Cessation
Alcohol-Related Disorders
Eligibility:
All Genders
18-70 years
Phase:
PHASE3
Brief Summary
Smoking is often a problem for alcohol dependent individuals. Many people who seek treatment for alcohol dependence are unable to quit smoking. The purpose of this study is to evaluate the effectivene...
Detailed Description
Past research suggests that over 75% of alcohol dependent individuals in early alcohol recovery smoke cigarettes; smoking-related mortality exceeds alcohol-related mortality in this population. Many a...
Eligibility Criteria
Inclusion
- Smokes a minimum of 10 cigarettes daily for at least 1 year prior to study entry
- Abstinence from alcohol and other non-nicotine drugs for between 1 and 12 months at time of study entry
- Meets criteria for alcohol dependence or abuse in the 12 months prior to study entry
Exclusion
- History of seizures, head trauma and/or severe hepatic cirrhosis
- Current use of medications known to affect smoking behavior and/or cessation
- Use of tricyclic antidepressant medication and monoamine oxidase inhibitors
- Major depressive disorder within the month prior to study entry
- Eating disorder within the year prior to study entry
- History of bipolar or psychotic disorder
- Pregnant or breastfeeding
- Unstable serious medical disorder
- History of migraines
- Currently using smokeless tobacco, pipes, or cigars
Key Trial Info
Start Date :
April 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
143 Patients enrolled
Trial Details
Trial ID
NCT00304707
Start Date
April 1 2005
End Date
February 1 2011
Last Update
May 15 2017
Active Locations (1)
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1
ENRM Veterans Hospital
Bedford, Massachusetts, United States, 01730