Status:
COMPLETED
Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
Lead Sponsor:
Montefiore Medical Center
Conditions:
Acute Pain
Eligibility:
All Genders
65+ years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the em...
Detailed Description
Pain is cited as the most frequent reason for visit to emergency departments (EDs) . It can be estimated from the National Hospital Ambulatory Medical Care Survey, an annual survey of a representative...
Eligibility Criteria
Inclusion
- Age greater than 65 years
- Pain with onset within 7 days
- ED attending physician's judgment that patient's pain warrants use of parenteral opioids
- Normal mental status
Exclusion
- Prior use of methadone
- Use of other opioids or tramadol within past seven days
- Prior adverse reaction to morphine or hydromorphone
- Chronic pain syndrome
- Alcohol intoxication
- Systolic Blood Pressure \<90 mm Hg
- Use of monoamine oxidase (MAO) inhibitors in past 30 days
- Elderly patients with a capnometry reading of greater than 46
Key Trial Info
Start Date :
July 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2007
Estimated Enrollment :
194 Patients enrolled
Trial Details
Trial ID
NCT00305058
Start Date
July 1 2005
End Date
March 1 2007
Last Update
August 20 2018
Active Locations (1)
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1
Montefiore Medical Center
The Bronx, New York, United States, 10467