Status:

COMPLETED

Assess the Immunogenicity of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine

Lead Sponsor:

GlaxoSmithKline

Conditions:

Infections, Streptococcal

Streptococcus Pneumoniae Vaccines

Eligibility:

All Genders

8-16 years

Phase:

PHASE3

Brief Summary

Evaluate the immune response of GSK Biologicals' 10-valent pneumococcal conjugate vaccine one month after completion of a 3-dose primary vaccination course administered at 2, 3, 4 months of age

Detailed Description

Test groups: 2 groups (60 subjects/group). 10Pn-PD-DiT group receiving GSK Biologicals' 10-valent pneumococcal conjugate vaccine + DTPa-HBV-IPV/Hib; Control group receiving Prevenar + DTPa-HBV-IPV/Hib

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Male or female between, and including, 8 and 16 weeks (56-118 days) of age at the time of the first vaccination, free of obvious health problems and with written informed consent obtained from the parent/guardian of the subject.
  • Exclusion criteria:
  • Use of any investigational or non-registered drug or vaccine other than the study vaccine within 30 days preceding the first dose of study vaccine, or planned use during the study period.
  • Planned administration/ administration of a licensed vaccine not foreseen by the study protocol during the period starting from one month before the first dose of vaccine(s) and during the entire study period.

Exclusion

    Key Trial Info

    Start Date :

    October 27 2005

    Trial Type :

    INTERVENTIONAL

    End Date :

    April 7 2006

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT00307541

    Start Date

    October 27 2005

    End Date

    April 7 2006

    Last Update

    January 2 2020

    Active Locations (32)

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    Page 1 of 8 (32 locations)

    1

    GSK Investigational Site

    Mannheim, Baden-Wurttemberg, Germany, 68167

    2

    GSK Investigational Site

    Marbach, Baden-Wurttemberg, Germany, 71672

    3

    GSK Investigational Site

    Nördlingen, Bavaria, Germany, 86720

    4

    GSK Investigational Site

    Tutzing, Bavaria, Germany, 82327