Status:
COMPLETED
Comparison of Airway Clearance Efficacy of Two High Frequency Chest Wall Oscillation (HFCWO) Devices in Cystic Fibrosis
Lead Sponsor:
University of Minnesota
Conditions:
Cystic Fibrosis
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Patients with cystic fibrosis (CF) must perform daily bronchial drainage therapy (BD) to keep their airways clear of secretions. Many different techniques are available to achieve this and there is cu...
Detailed Description
Participation in the study will be for 4 days. During initial subject recruitment, investigators will review inclusion and exclusion criteria with potential subjects. Upon enrollment, qualifying subje...
Eligibility Criteria
Inclusion
- Diagnosis of CF established by sweat chloride \> 60 mmol/L.
- Age older than 18 years.
- History of chronic daily sputum production.
- Currently on a home therapeutic regimen that includes some form of BD performed at least 2 times daily that also includes concomitant use of an inhaled mucolytic and inhaled bronchodilator.
- FVC and FEV1 \> 40%-predicted, and with stable lung function (no greater than a 10% variation in lung function parameters over the preceding 4 months).
- Evaluated at the University of Minnesota CF Center 3 or more times in the preceding 12 months.
Exclusion
- Hospitalization for CF pulmonary complications in the 2 months preceding enrollment.
- Hemoptysis \> 60 cc in a single episode in the 4 weeks preceding enrollment.
- Chronic chest pain.
- Participation in another clinical trial in the previous 30 days.
- Use of intravenous antibiotics in the 2 months preceding enrollment.
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
End Date :
August 1 2006
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00308958
Start Date
February 1 2006
End Date
August 1 2006
Last Update
May 30 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Minnesota Medical Center
Minneapolis, Minnesota, United States, 55455