Status:

COMPLETED

Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Chronic Nonmalignant Pain

Lead Sponsor:

Purdue Pharma LP

Collaborating Sponsors:

Napp Pharmaceuticals Limited

Conditions:

Chronic Non-malignant Pain

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The objective of this study is to demonstrate the effectiveness and tolerability of the buprenorphine transdermal system (5, 10 and 20) in comparison to matching placebo transdermal system in subjects...

Detailed Description

Buprenorphine is a synthetic opioid analgesic with over 25 years of international clinical experience indicating it to be safe and effective in a variety of therapeutic situations for the relief of mo...

Eligibility Criteria

Inclusion

  • At least 2 month's history of nonmalignant pain, currently in stable pain control on opioid therapy.
  • Good, very good or excellent pain control on current opioid therapy.
  • Willing and able to use a telephone interactive voice response service.

Exclusion

  • Currently receiving daily morphine or oxycodone monotherapy.
  • Scheduled for surgery of the disease site (eg, major joint replacement surgery), or any other major surgery, which would fall within the study period.
  • Other protocol-specific exclusion/inclusion criteria may apply.

Key Trial Info

Start Date :

March 1 2001

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2001

Estimated Enrollment :

267 Patients enrolled

Trial Details

Trial ID

NCT00312195

Start Date

March 1 2001

End Date

July 1 2001

Last Update

September 10 2012

Active Locations (42)

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Page 1 of 11 (42 locations)

1

Hawthorne and York

Phoenix, Arizona, United States, 85008

2

Arizona Research Center Inc

Phoenix, Arizona, United States, 85023

3

Clinical Research Consultants Inc

Trumbull, Connecticut, United States, 06611

4

Tampa Bay Medical Research Inc

Clearwater, Florida, United States, 33761