Status:
COMPLETED
Intra-coronary Infusion of Bone Marrow Derived Autologous CD34+ Selected Cells in Patients With Acute Myocardial Infarction
Lead Sponsor:
Emory University
Collaborating Sponsors:
Texas Heart Institute
Conditions:
Myocardial Infarction
Coronary Artery Disease
Eligibility:
All Genders
18-75 years
Phase:
PHASE1
Brief Summary
Following a Heart attack the acute loss of heart muscle cells results in a cascade of events causing an immediate decrease in cardiac function that has the potential to persist long term. Despite reva...
Eligibility Criteria
Inclusion
- Age 18 - 75 years.
- Acute ST elevation myocardial infarction meeting ACC/AHA criteria, with symptoms of chest pain within 3 days of admission. Criteria include (ST elevation \> 1mm in limb leads or 2 mm in two or more precordial leads and increased levels of troponin, CPK MB or both)
- NYHA heart failure class of I, II or III
Exclusion
- Patients who are not candidates for percutaneous intervention, conscious sedation, MRI, SPECT imaging or mini-bone marrow harvest
- History of sustained chest pain unrelieved by nitrates, occurring 4 or more days before revascularization.
- Patients who fail to re-perfuse the infarct related coronary artery or have successful stent placement
Key Trial Info
Start Date :
March 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2013
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT00313339
Start Date
March 1 2006
End Date
March 1 2013
Last Update
November 18 2013
Active Locations (1)
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1
Emory University
Atlanta, Georgia, United States, 30326